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However, the authors mention that TA-1 treatment for hepatitis B is “now obsolete” due to the discovery of direct antiviral agents.7 Though it doesn’t appear to be useful as a monotherapy for hepatitis C, TA-1 combined with interferon alpha 1 showed “superiority” over interferon alpha monotherapy

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A study performed with 1354 elder Australian subjects showed an association between low vitamin B 12 levels and cognitive impairments that was enhanced in the presence of high folate intake (Moore et al., 2014)