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[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin

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Mean HbA1c reduction with cagrisema was also greater compared to semaglutide 2.4 mg and cagrilintide 2.4 mg alone (−2.2% vs