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For crystallization of ShHTL4, 0.40 μL of protein solution (18.0 mg mL −1 ) was mixed with 0.40 μL of reservoir solution containing 90 mM Tris (pH 9.0), 180 mM MgCl 2 , 27% (w/v) PEG4000, and 1 mM GSH and incubated at 20 °C

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Astrocytes, on the other hand, grant trophic support, release factors which stimulate both differentiation of OPCs into oligodendrocytes, and may induce recruitment and migration of those cells in events of remyelination