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Loss of this receptor completely blocks stress-induced hair graying.23 Other stress-related mediators include calcitonin gene-related peptide, which maintains immune privilege and induces catagen while promoting melanogenesis

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The Quercetin Paradox This duality in quercetin—and its potential to be metabolized down one of two very different pathways—is known as the "quercetin paradox." Because quercetin can oxidize so easily, forming pro-oxidant, toxic metabolites, special care must be given to how quercetin-containing products are formulated