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Furthermore, the various orientations of both the substrates and UCEs in the modeled structures suggest that the different UCEs may have preferences to transfer ubiquitin to one type of substrate (e.g., neosubstrate) over another (e.g., native)

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When undetected, NIS1 effectors have been shown to modulate several defence pathways in planta by targeting factors involved in signal transduction and ROS production ( N