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Placental extracts are rich in growth factors G-CSF, GM-CSF, EGF, FGF, HGF, IGF, PDGF, TGF, VEGF which show an array of physiological effects ranging from immunomodulation, anti-inflammatory, wound healing, cellular proliferation and regeneration (Table 1) [42,50-52]

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These data suggest that chronic stress accelerates cellular aging through inducing increased levels of ROS [50]

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