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9.2.12 Summary of evaluations Toluidine blue has been recommended in a number of studies as being preferable to methylene blue on the grounds of superior efficacy (Daunderer, 1979, 1980

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Since human hallmarks of sarcopenia are recapitulated in aged (24-month-old) mice, we treated mice from 22 to 24 months of age with NNMTi, intensive exercise, or a combination of both, and compared skeletal muscle adaptations, including grip strength, longitudinal running capacity, plantarflexor peak torque, fatigue, and muscle mass, fiber type, cross-sectional area, and intramyocellular lipid (IMCL) content