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Taken together, the published studies underscore the potential of EA as a natural antifungal agent and adjuvant to conventional therapies, although dedicated pharmacokinetic and formulation studies are still needed to confirm its safety and efficacy in clinical settings

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Peak concentrations, typically measured 30 min after completion of the intravenous infusion, serve as surrogates for concentration-dependent bactericidal activity, as reflected in the Cmax/MIC ratio