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While EECp failed to downsize bladder edema with the comparable efficiency of mesna, it enhanced significantly the histopathological scores and diminished myeloperoxidase activity in the lung, as well as, the levels of malondialdehyde in the bladder, lung, and spleen tissue

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Experimental studies suggest that DSIP may interact with multiple signalling mechanisms, including NMDA receptor–related pathways and MAPK-associated signalling cascades, with observed effects dependent on concentration, exposure duration, and experimental context