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The 18β-glycyrrhetinic acid (18β-GA) in Xiaoyaosan (XYS), which is a traditional Chinese medicine and used for the treatment of depression, has been identified as a primary active compound [44]

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The schematic in Figure 2C captures the sequential progression of hallmark AD features, such as amyloid plaques, tau tangles, neuronal loss, gliosis, synaptic degeneration, and cognitive decline