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Notably, redox-sensing cysteine residues (i.e., thiol switches) provide an orthogonal control system to modulate activity of cellular and physiological mechanisms [17]

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In summary, our results establish an important functional role of VEGF in hair biology and identify a paracrine mechanism by which the proliferative epithelial compartment of the hair follicle, that in itself is not vascularized, induces enhanced vascular support to meet its highly increased nutritional needs during the anagen growth phase