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Oxidative stress, which arises when production of free radicals exceeds their neutralization, is a common complication of chronic inflammation and can have detrimental effects on the integrity of the BBB and further perpetuate inflammatory responses within the brain (Schreibelt et al., 2007
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Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child
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