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Preclinical research in murine senescence models has examined FOXO4-DRI for its capacity to reduce senescent cell burden, with observed improvements in physical function, coat density, and renal histology endpoints in aged subjects
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69 miRNAs could be used as clinical biomarkers to predict the development of obesity and related complications or to assess therapeutic anti-obesity strategiesβ effectiveness due to the normalization of miRNAs levels upon acute weight loss
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