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Another animal study noted that iron supplementation worsens steatohepatitis with increased liver enzymes, steatosis, and hepatic inflammation [67]

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Furthermore, immunofluorescence of Caveolin 1 (Caveolin 1-positive vessels in the placental labyrinth assess placental vascularization and respond to placental vascular endothelial damage 22,23 ) on the cross-sections of placenta displayed that Erastin led to significantly reduced vascular density, indicated that Erastin could result in endothelial damage (Fig