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However, long-term NNMT inhibition in humans hasn't been characterized beyond small pilot cohorts, so concerns about sustained NAD+ elevation (which could theoretically promote certain cancers via PARP or SIRT activation) remain speculative but unresolved

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(9) Further, preliminary research involving CJC-1295 (Mod GRF 1-29) 1-29 indicates a potential rise in nocturnal growth hormone levels, as well as serum levels of IGF-I and IGFBP-3, and GHBP concentrations