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P i (upper case) is the macro partition coefficient, where subscript i refers to the ionization state of species included in P i

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In this model, GHK inhibited pulmonary fibrosis by suppressing the TGF-β1/Smad2/3 signaling pathway — the central driver of fibrotic matrix deposition — while simultaneously reducing epithelial-to-mesenchymal transition and inflammatory cytokine production