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That said, a clean mouse safety signal is not equivalent to a human safety profile: no published human trials exist to characterise dosing tolerability, side effects, or long-term safety in people, and that gap should be treated as a genuine unknown rather than an assumed non-issue

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doi: 10.3904/kjim.1993.8.1.8, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Associated Data This section collects any data citations, data availability statements, or supplementary materials included in this article