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The conserved region in the middle (CRIM) of Sin1 is a domain that has been shown to mediate recruitment of AGC kinases to mTORC2 and thus required for their mTORC2‐mediated activation (Tatebe et al., 2017)

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the treatment of diseases by TCM monomers by affecting ferroptosis can be manifested by the degree of lipid peroxidation, the degree of iron accumulation, and so on, which may be a better way of observing ferroptosis

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