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Cartilage & Joint Protection Because DSIP is often studied for sleep regulation , it is natural to compare it with melatonin , the most widely used sleep supplement: AOD-9604 demonstrated chondroprotective effects in models of cartilage degradation.⁴ May reduce proteoglycan loss and support collagen maintenance

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That dual mechanism is central to the CagriSema FDA review, because it is the first time the FDA has been asked to evaluate a GLP-1 and amylin combination in a single fixed-dose product