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In enterocytes, claudin-2 and claudin-15 are the dominant paracellular monovalent cation and water channels, with different degrees of expression
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StRIP14 containing two i, i+4 staples on the same helix face and an overall net negative charge of −4 was the most stable, but in order to reduce the negative charge, some Asp and Glu residues were mutated to Asn and Gln, respectively
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