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(2026) doi: 10.1038/s12276-026-01650-1
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(in)GSH has been used as a potential route of central nervous system (CNS) glutathione augmentation since 2004, based on an acceptable safety and tolerability profile, 17, 18 biological plausibility that small, polar molecules may bypass the blood-brain barrier (BBB) via intranasal administration, and anecdotal case reports of improvement
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