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and rats in the low-dose group, medium-dose group, and high-dose group of Cur-NCs were intraperitoneally injected with 100, 200, and 400 μg/kg of Cur-NCs daily ( Enzyme-linked immunosorbent assay (ELISA) Levels of LDH (A020-2-2, Nanjing Jiancheng, China), MDA (MM-0436H, Jiangsu Meimian Industrial Co., Ltd., China), Iron (Fe 2+ , BC5310, Solarbio, China), and GSH (MM-0458H, Jiangsu Meimian Industrial Co., Ltd., China) in the cultured HK-2 cells, as well as the levels of MDA, SOD, Cat, and GSH (MM-0385R2, MM-0386R1, MM-20447R1, MM-0602R1