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The accumulation of lipids leads to lysosomal membrane permeabilization (LMP), which contributes to lipid-ROS production and cathepsin B (CTSB) release [47]

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273 Other small molecule activators and inhibitors of calcium channels have been identified, including compounds targeting ORAI/STIM, 274−280 voltage gated channels 281−288 and others (Table 4)

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