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On two different occasions in a cross-over, balanced fashion the subjects were administered orally either a single dose of NAC 600 mg as effervescent tablets or 4 repeated doses of NAC as granules in sachets at the regimen of 200 mg t.i.d
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The inclusion of both reference and clinical strains enhances the translational relevance of the study and allows assessment of antimicrobial efficacy under both standardized and real-world clinical conditions
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