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When we rank-ordered host genes by their median robust z-scores (measure of deviations from the median), we found a wide range of genes for which Cas9-assisted knockout either reduced or promoted parasite growth, parasite development, or actin recruitment to parasite vacuoles (Figs 1B-D)
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Some patients may experience: Mild injection site reactions (redness, slight swelling) Temporary drowsiness (related to increased melatonin production) Mild headache in the first few days Serious adverse effects are rare in published literature
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