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This allows senescent cells to persist, contributing to chronic inflammation and age-related diseases (3)

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Collagen and ECM remodeling: In fibroblast cell culture studies, GHK-Cu has been shown to upregulate collagen I and collagen III gene expression and simultaneously stimulate matrix metalloproteinase (MMP) activity, particularly MMP-2 and MMP-9, enabling simultaneous synthesis and remodeling of extracellular matrix