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BDV: Borna Disease In fact, the total number of non-redundant genes encoded by the microbiota far exceeds that of the human host, and the composition and function of the microbiota are significantly influenced by environmental factors ( A growing number of studies indicate that levels of natural antibodies against Gram-negative bacteria and lipopolysaccharide (LPS), such as IgA, IgM, and IgG, are elevated in patients with SZ