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Biochem Pharmacol (2000) 59:317–20.10.1016/S0006-2952(99)00177-X 46 OkadaSLiQWhitinJCClaybergerCKrenskyAM

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In another embodiment the ligand is a ligand that is endocytosed and/or transcytosed into and/or through the target cell as may be assayed by a cell culture model of the BBB (using primary isolated bovine brain capillary endothelial cells (BCEC)) as described by Gaillard et al

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