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Recent studies have linked TXN system damage with hyperoxic injury and abnormal lung development, noting that the TXN system not only has a simple ROS detoxification function but also acts as a REDOX sensor when oxygen concentration changes, assisting newborns to complete the oxygen concentration conversion process from intrauterine relative hypoxia to hyperoxia exposure (67)

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The molecular docking confidence score of GhGPX4 and GhGSTF6 was 0.8951 ( Supplementary Figure 9a ), and that of GhGPX4 and GhDHAR2 was 0.7111 ( Supplementary Figure 10a )