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They work by: Slowing gastric emptying , which prolongs feelings of fullness Reducing appetite through effects on brain centres that regulate hunger Improving insulin secretion and glucose metabolism Potentially reducing food intake and affecting eating behaviours These injections are administered subcutaneously, typically once weekly (semaglutide) or once daily (liraglutide), and have been approved by the MHRA for weight management in adults with a BMI ≥30 kg/m², or ≥27 kg/m² with weight-related comorbidities, as an adjunct to reduced-calorie diet and increased physical activity
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10.7554/eLife.02523 31 Do VanB.GouelF.JonneauxA.TimmermanK.GeléP.PétraultM.et al (2016)
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