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80 Therefore, clinicians should raise their index of suspicion for this malignancy and lower their biopsy threshold in HS patients to prevent or minimize SCC metastasis especially when ulcerative lesions, chronic wounds, nodules, or ulcerative nodules arise and do not show response to common antibiotic or immunosuppressive treatments used in HS patients

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However, in the substantia nigra of PD patients, glutathione levels as well as the activities of SOD, catalase, and GPX have been shown to be decreased [151], rendering the cells more vulnerable to oxidative stress