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Nonetheless, clinical studies have demonstrated that lesinurad at a dosage of 200 mg once daily does not elevate the risk of renal, cardiovascular, or other adverse events beyond those associated with xanthine oxidase (XO) inhibitors alone, with the exception of transient increases in serum creatinine levels
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Just like the “two hit” concept of PD, the COVID-19 infection might have served as an infectious second hit [52]
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