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The GSTM1 gene test analyses DNA for a common insertion/deletion variant that determines whether you produce functional glutathione S-transferase Mu 1 enzyme or have a "null" genotype with no enzyme activity

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Ob/ob mice usually exhibit extreme overweight, hyperphagia, hyperinsulinism, hyperglycemia, and insulin resistance and continue developing spontaneous hepatic steatosis [62] but do not progress to steatohepatitis