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173 Subsequently, novel mutant IDH1 R132H inhibitors has been reported, such as AG-120, AG-881, ML309, 174 2-(3-trifluoromethylphenyl)isothioazol-3(2H)-one, 175 bis imidazole phenol (cpd 1), 176 1-hydroxypyridin-2-one compounds 177 and GSK321 and GSK864 178 (Table 1)
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