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coli K12, to produce a human growth hormone precursor (MAE-hGH) and found that, in HKSII medium (pH 7.2) containing 5 g/L glucose, acetate addition resulted in inhibition of cell growth at concentrations from 6 g/L (100 mM), but a significant decrease in the specific production rate of MAE-hGH at concentrations from 2.4 g/L (40 mM) [30]
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