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injections of 100 nmol kg −1 MK-801 ( n = 8 mice), 100 nmol kg −1 GLP-1 ( n = 8 mice), 100 nmol kg −1 GLP-1–MK-801 ( n = 8 mice) or vehicle (isotonic saline, n = 8 mice) at a volume of 5 µl g −1

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If the CEP is damaged or denatured, it may lead to the outflow of water from the NP under heavy loads, resulting in the denaturation of the NP (23)