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How Tesofensine Works: Triple Neurotransmitter Action Tesofensine is classified as a monoamine reuptake inhibitor , meaning it blocks the reabsorption of key neurotransmitters in the brain: Dopamine Norepinephrine Serotonin By inhibiting their reuptake, Tesofensine increases the availability of these neurotransmitters in the synaptic cleft, leading to enhanced signaling
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