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Cagrilintide: The Long-Acting Second-Generation Amylin Analog Cagrilintide (also written as AM-833) is a second-generation amylin analog developed specifically to address pramlintide's short half-life
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High doses, or inadvertent intravascular injection, have led to high plasma levels and related depression of the myocardium, decreased cardiac output, bradycardia, heart block, ventricular arrhythmias, and cardiac arrest [see Warnings and Precautions (5.4)]
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