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The conclusion is that the trispecific SAR442257 operates via dual targeting of CD38 and CD28 on myeloma cells and of CD3 and CD28 on T lymphocytes, showing superior MM killing compared to bispecific antibodies

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and the UBC proteomics core facility team—Jason Rogalski, Renata Moravcova, and Jeanne Yuan—for running the mass spectrometry samples, instrument maintenance, and technical expertise