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Where this leaves the evidence The signal from the randomised data is coherent: predominantly gastrointestinal effects, front-loaded during titration, mostly mild to moderate, a measured excess of injection-site reactions, and a monotherapy discontinuation rate that did not exceed placebo — alongside a serious-adverse-event rate that was numerically higher on cagrilintide alone (8.9%) than on placebo (6.1%) or semaglutide alone (5.0%)
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doi: 10.3390/cells10010047 142 PearsonJ
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