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While FOXO1, 3, and 4 are inactivated via their translocation from the nucleus to the cytoplasm after AKT phosphorylation, the FOXO6 isoform remains in the nucleus regardless of its phosphorylation state [77, 125]
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It also examines the potential of peptides like Epithalon and DSIP in regulating circadian rhythms and improving sleep quality
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